Tag Archives: ApoE4-gene

Are women more likely to develop Alzheimer’s?

By: Dr. Pascale Michelon

In the US, two-third of the people diagnosed with the disease are women. The reason why is not clear so far. Of course, women are more likely than men to live long enough to develop the disease.  But there may be other factors such as a gene (APOE4) or the hormone estrogen. This NPR story helps us understand this a little bit better. Continue reading

How Do Genes Affect Alzheimer’s Risks?

By: Dr. Pascale Michelon

Although there is a strong association between the ApoE4 gene and the risk of developing late-onset Alzheimer’s Disease, researchers do not know what role this gene plays in the disease. A recent study provides new clues: in mice, ApoE4 damages the blood vessels that provide nutrients to the brain. Continue reading